Immediately receive sections as slim or thick as your application demands, without having stressing about getting rid of or distorting valuable tissue samples.
Megatome is often a vibrating microtome intended to section a wide selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables high-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue harm and information reduction.
Antibodies could acquire months to diffuse by only some millimeters of tissue, which has a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and incorporates a exclusive deflection Management mechanism.
SE takes advantage of a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all through a porous sample without harming electrically billed constructions within the tissue. This permits 2-four working day clearing of intact organs,
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Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data loss.
eFLASH can be a speedy tissue labeling technique that enables for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed all over intact tissue volumes, although its modular style allows you to improve and personalize specific factors.
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Leverage the Very clear+ tissue clearing method, coupled with eFLASH and patented stochastic electrotransport technologies, to swiftly obvious and label total organs. Key highlights and attributes contain:
Our novel Defend tissue preservation system sorts intramolecular bonds utilizing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.